Asymmetric Hydrogenation

نویسنده

  • Tsuneo Imamoto
چکیده

The asymmetric hydrogenation of prochiral unsaturated compounds, such as alkenes, ketones, and imines, is one of the most efficient and straightforward methods for the preparation of optically active compounds. This method uses dihydrogen and small amounts of chiral transition metal complexes and is now recognized as economical, operationally simple, and environmentally friendly. It is frequently used in both academia and industry for the synthesis of chiral amino acids, amines, alcohols, and alkanes in an enantiopure or enantiomerically enriched form.

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تاریخ انتشار 2017